منابع مشابه
Targeting of Synthetic Gene Delivery Systems
Safe, efficient, and specific delivery of therapeutic genes remains an important bottleneck for the development of gene therapy. Synthetic, nonviral systems have a unique pharmaceutical profile with potential advantages for certain applications. Targeting of the synthetic vector improves the specificity of gene medicines through a modulation of the carriers' biodistribution, thus creating a dos...
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Glioma has been considered to be the most frequent primary tumor within the central nervous system (CNS). The complexity of glioma, especially the existence of the blood-brain barrier (BBB), makes the survival and prognosis of glioma remain poor even after a standard treatment based on surgery, radiotherapy, and chemotherapy. This provides a rationale for the development of some novel therapeut...
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The range of bioactive substances emerging as potential drug candidates, together with those currently under research and development, continue to provide major challenges for efficient drug delivery and targeting. Various strategies for formulation design using diverse chemicals as formulation excipients are available, and numerous materials are being considered and developed to provide specif...
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ژورنال
عنوان ژورنال: Future Medicinal Chemistry
سال: 2019
ISSN: 1756-8919,1756-8927
DOI: 10.4155/fmc-2019-0152